Fertilizers can sustainably enhance agriculture for improving nutrition and health, said the participants of the second seminar in the lead-in series for the 2020 conference. Luc Maene of the International Fertilizer Association (IFA), Tom Bruulsema of the International Plant Nutrition Institute (IPNI), and Ross Welch from USDA’s Agricultural Research Service (ARS) explored both the potential opportunities and major challenges for using fertilizers and other technologies to positively affect agriculture, health, and nutrition.